Texas A&M University

Clinical Pathology

clinical-path-2 The Texas A&M Institute for Preclinical Studies Clinical Pathology Laboratory provides clinical pathology and diagnostic data to support preclinical research utilizing a variety of different animal species.  The laboratory operates according to FDA Good Laboratory Practices (GLP) for Nonclinical Laboratory Studies and is staffed with board certified laboratory personnel.


Chemistry

  • An automated chemistry-immuno analyzer is used for high throughput analysis of serum, plasma, urine, CSF, and other body fluids
  • Comprehensive 125 test menu of blood chemistry, specific protein, and therapeutic drug assays
  • Open reagent system allowing for easy addition of third party research assays

Hematology

  • An automated hematology analyzer is validated for performing complete blood counts (CBC) on whole blood specimens
  • Configured with a veterinary package for analyzing specimens from multiple animal species
  • Automated 5-part white blood cell (WBC) differentials are determined in addition to manual WBC differentials by experienced laboratory staff

Hemostasis

  • Automated hemostasis analyzer is utilized for a variety of both coagulation and fibrinolytic assays
  • Uses clotting, chromogenic, and immunologic assay capabilities to perform a wide range of routine as well as specialty coagulation/fibrinolytic tests
  • Point-of-care hemostasis devices are also available to perform bedside/surgery coagulation assays

Immunology

  • For quantifying numerous analytes and biomarkers (cytokines, etc.), a multiplex array system using Luminex xMAP technology is utilized
  • Preconfigured or custom arrays available with the possible capability of detecting up to 100 different analytes in one single specimen
  • Expertise with traditional diagnostic methods such as ELISAs and other microplate assays

Lab Throughput & Capabilities

  • A laboratory information system (LIS) electronically tracks workflow throughout the clinical pathology laboratory
    • All facets of specimen handling from collection, testing, storage, final result delivery, and result archiving are handled by the LIS
    • Barcoded specimens are assayed via analyzer/LIS interfaces that result in a complete data audit trail and minimize the risk of data transcription errors
    • Historical reference intervals, reagent usage, quality control review, and long term specimen storage are all managed and standardized by the laboratory computer system
  • Validated assays for bovine, canine, caprine, mouse, ovine, porcine, and rat specimens
  • Ability to add and validate additional species upon request
  • Trained and experienced in numerous additional diagnostic methodologies for future laboratory and test menu expansion